Assessment of the efficacy of uterine artery Doppler in predicting the response to Mefenamic acid during treatment of women having IUCD associated menorrhagia
Background: Bleeding with IUCDs is considered iatrogenic dysfunctional uterine bleeding. The bleeding associated with IUCD use may either occur during menstruation (heavy and/or prolonged) or in the form of intermenstrual bleeding and spotting. Patients and Methods:This study was carried out on 156 women attended the family planning out-patient clinic in the Obstetrics and Gynecology Department, Ain-Shams University Hospitals, during the period from May 2017 to May 2018. Patients were divided according to the response to treatment into two groups: Group (I): Responders to treatment with Mefenamic acid and Group (II): Non-responders to treatment with Mefenamic acid. Response to treatment was evaluated according to: Pictorial blood loss assessment chart. Results: Interpretation of the results of this work showed that uterine artery mean value of the PI of the women who responded to treatment with Mefenamic acid (group I) (1.54±0.42) were significantly higher than mean value of PI of women who didn’t respond to treatment with Mefenamic acid (group II) (0.96±0.28), also showed that uterine artery mean value of the RI of the who responded to treatment with Mefenamic acid (group I) (1.01±0.25) were significantly higher than mean values of RI of women who didn’t respond to treatment with Mefenamic acid (group II) (0.71±0.21). Doppler indices showed that pulsatility index ≥ 1.27 had moderate sensitivity (75.3%) and NPV (75.3%) but high specificity (90.1%) and PPV (90.1%) in prediction of responders. Resistive index ≥ 0.93 had low sensitivity (69.4%) and NPV (70.8%) but moderate specificity (88.7%) and PPV (88.1%) in prediction of responders. Conclusion:There is a strong relationship between uterine artery Doppler indices and prediction of response to Mefenamic acid.
Sammour, H., Ashoush, S., Ibrahim, O., & ESSAM, Y. (2020). Assessment of the efficacy of uterine artery Doppler in predicting the response to Mefenamic acid during treatment of women having IUCD associated menorrhagia. Evidence Based Women's Health Journal, 10(1), 104-111. doi: 10.21608/EBWHJ.2019.19364.1054
MLA
Hazem M. Sammour; Sherif A. Ashoush; Osama I. Ibrahim; YASMINE ESSAM. "Assessment of the efficacy of uterine artery Doppler in predicting the response to Mefenamic acid during treatment of women having IUCD associated menorrhagia", Evidence Based Women's Health Journal, 10, 1, 2020, 104-111. doi: 10.21608/EBWHJ.2019.19364.1054
HARVARD
Sammour, H., Ashoush, S., Ibrahim, O., ESSAM, Y. (2020). 'Assessment of the efficacy of uterine artery Doppler in predicting the response to Mefenamic acid during treatment of women having IUCD associated menorrhagia', Evidence Based Women's Health Journal, 10(1), pp. 104-111. doi: 10.21608/EBWHJ.2019.19364.1054
VANCOUVER
Sammour, H., Ashoush, S., Ibrahim, O., ESSAM, Y. Assessment of the efficacy of uterine artery Doppler in predicting the response to Mefenamic acid during treatment of women having IUCD associated menorrhagia. Evidence Based Women's Health Journal, 2020; 10(1): 104-111. doi: 10.21608/EBWHJ.2019.19364.1054
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