Pregnancy Rate After Fresh Embryo Transfer Versus Vitrified-Thawed Embryo Transfer Cycles: Minia University Experience

Objective: To study pregnancy rates after vitrified-thawed embryo transfer and fresh embryo transfer.
Design: Retrospective study.
Setting: Infertility and IVF unit, Minia University Hospital.
Patients and Methods: All women undergone ICSI program during the period from first of January 2010 to December 2014, pregnancy rate was compared between two groups, first group (Group I) had fresh embryo transfer, the second group (Group II) had vitrified –thawed embryo transfer .
Main outcome: Clinical pregnancy rate.
Results: There was insignificant difference between two groups regarding chemical pregnancy rate it was 228 (43%) in (Group I), 36% (186) in the second group (Group II). Clinical pregnancy rate 24.5 % (130) versus 22.1% (114). Implantation rate 28.6 % versus 24% . The rate of single pregnancy was higher in the first group 80% than in the second group 76.4% . The rate of twins was higher in the second group 23.6 %.
Conclusion: A program of vitrified-thawed embryo transfer should be adopted by all IVF center especially in low-income countries to maximize the benefit of the single treatment cycle, increase cumulative pregnancy rate and decrease the cost of repeated cycle stimulation, as the pregnancy rate is almost equal in FET and fresh embryo transfer