Menstrual bleeding profile, adverse effects and effectiveness of an etonogestrel subdermal implant: A prospective study

Document Type : Original Article

Authors

1 Obstetric and gynecology, faculty if medicine, Mansoura university, Mansoura, Egypt

2 Department of Obst. and Gyn. Faculty of medicine Mansoura University

3 Mansoura Faculty of medicine Obst. and Gyn. Department

4 Obstetric and Gynecology, faculty of medicine, Mansoura University, Egypt

Abstract

Objective: The aim of the study is to evaluate menstrual bleeding profile, adverse effects and effectiveness of an ENG implant (Nexplanon NXT) in healthy females during the first year of application.

Methods: This was a prospective observational study carried on Obstetrics& Gynecology department in Mansoura University Hospitals and Fertility Care Unit from April 2019 to April 2020. Including 95 healthy women of all ages who desired for long-term contraception by using ENG implant (Nexplanon NXT). Follow-up visits were every 90 days periods over 12 months after insertion of the implant, for bleeding pattern, BMI, and side effects.

Results: There was a statistically significant increase in BMI during follow up from 27.84±3.37 kg/m2 at baseline that increased to 29.43±3.75 kg/m2 at 4th visit. There was a statistically significant difference of bleeding abnormalities between first and fourth visit, between second and fourth visit. Insertion site pain was detected among 10.5% at 1st visit only. None of the studied cases have become pregnant during all visits.

Conclusion: We concluded that etonogestrel subdermal contraceptive implants are relatively safe with minimal side effects and high efficacy. However, the major side effects associated with implants use are weight gain and bleeding abnormalities.

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