The Effect of Laparoscopic Ovarian Drilling on Anti-Müllerian Hormone, LH/FSH Ratio and Inhibin B

Document Type : Original Article

Authors

1 Ob and gyne ain shams university Cairo Egypt

2 Faculty of Medicine, Ain-Shams University

3 El-Galaa Maternity Teaching Hospital

Abstract

Aim: This study aimed to compare AMH to other parameters of ovarian reserve (OR) in evaluating the effect of laparoscopic ovarian drilling (LOD) on OR in treatment of PCO.
Results: The mean AMH level before the operation was 6.9±1.4 ng/ml and 8.2±1.4 ng/ml for the patients who got pregnant and those who did not get pregnant respectively. While the mean AMH level after 3 months of the operation was 5.1±1.1 ng/ml and 6.3±1.4 ng/ml for the patients who got pregnant and those who did not get pregnant respectively. The mean LH/FSH ratio before the operation was 2.04±0.5 and 3.02±0.6 for the patients who got pregnant and those who did not get pregnant respectively. While the mean LH/FSH ratio after 3 months of the operation was 1.15±0.2 and 1.93±0.6 for the patients who got pregnant and those who did not get pregnant respectively. The mean inhibin B level before the operation was 52.5±2.2 pg/ml and 52.6±3.9 pg/ml for the patients who got pregnant and those who did not get pregnant respectively. While the mean inhibin B level after 3 months of the operation was 48.3±2.1 pg/ml and 49.1±3.6 pg/ml for the patients who got pregnant and those who did not get pregnant respectively.
Conclusion: Pregnancy rates were significantly related to the preoperative LH/FSH ratio and AMH levels when comparing the cases that got pregnant with the cases who did not conceive postoperatively in patients of polycystic ovary syndrome (PCOS), whereas preoperative Inhibin B level had no relation to pregnancy rates.

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