2024-03-29T07:21:00Z
https://ebwhj.journals.ekb.eg/?_action=export&rf=summon&issue=14472
Evidence Based Women's Health Journal
2090-7265
2090-7265
2020
10
2
Does E-Coli play an important role in neonatal sepsis in preterm prelabour rupture of membrane?
Ameer
Elsherief
Adel
Ahmed
Aim: The aim of this study was to detect the most common causative organism causing neonatal sepsis in women suffered preterm prelabour rupture of membranes and if it is different from that of the maternal genital swab.Materials and Methods: This study was carried out on 200 pregnant women with PPROM at gestational age between 23 weeks plus 6 days to 28 weeks. Genital swabs were taken for microbiological study and all women were managed conservatively. After delivery, buccal and nasal swab were taken from the neonates and the detected organism(s) were correlated with those detected from the mothers' swabs. Also, neonatal outcome was studied regarding incidence of neonatal sepsis, Neonatal Intensive Care Unit) admission and neonatal mortality.Results: From the 200 enrolled cases and their neonates, there were thirty-three neonates (16.5%) that were admitted to the NICU with twenty-one neonates (67.8%) of them suffering neonatal sepsis. Only thirteen neonates (61.9%) of those who had suffered sepsis shared the same organisms with their mothers. The other eight cases (38.1%) had different organisms. The most frequent organism regarding maternal vaginal swabs was Escherichia coli followed by Group B Streptococci sharing the same frequency with non-hemolytic Streptococci, Staphylococcus aureus and Group A streptococci sharing the same frequency with Klebsiella species.Conclusion: E-coli is the most common causative organism for neonatal sepsis in PPROM before 28 weeks of gestation.
Chorioamnionitis
Neonatal sepsis
PPROM
2020
05
01
121
126
https://ebwhj.journals.ekb.eg/article_96090_da1321ca0d513a932e37e59b978a9d70.pdf
Evidence Based Women's Health Journal
2090-7265
2090-7265
2020
10
2
The relation between vitamin D level in the third trimester and preeclampsia
shaema
alsaeed
Nahed
Mohammed
Aziza
Nassef
Asmaa Abd Elsalam
Almadbouly
Introduction: Preeclampsia (PE) affects 2%–8% of all pregnancies and remains a leading cause of maternal and perinatal mortality and morbidity. Vitamin D was considered important for bone and calcium. There is some evidence now that low levels of Vitamin D are associated with the risk of preeclampsia but more studies are needed to prove the same.Aim of the work: The aim of our study was to assess the relation between the vitamin D deficiency and the occurrence of preeclampsia in the third trimester of pregnancy.Patients and Methods: This is a prospective case control study, where 90 pregnant women between 27-40 weeks of gestation were recruited from the outpatient clinic in Al zahraa university hospital, they subjected to 25(OH) vit D level estimations and transabdominal ultrasound. Follow up was done till delivery to assess occurrences of preeclampsia and assessment of fetal outcome. Cases were divided into control (n=30) and preeclampsia (n=60) groups. According to the severity, the preeclampsia cases were subdivided to mild (n=40) and severe preeclampsia(n=20)..Results: The two groups (PE and Control ) were comparable regarding maternal age, BMI and gestational age. There was significant relation between deficient 25-(OH) vitamin D and BMI. Patients with severe preeclampsia had significant lower level of 25-OH D than the mild preeclampsia and normotensive patients. There was no significant difference in 25(OH)vit D level between mild preeclampsia and control group.Conclusion: there were significant association between vitamin D deficiency and severe preeclampsia. Vitamin D deficiency may be a risk factor for preeclampsia and may be helpful for prediction of preeclampsia and its severity.
Deficient 25-OH vit D
25(OH) vitamin D
preeclampsia
2020
05
01
127
132
https://ebwhj.journals.ekb.eg/article_96096_de6e929e5204c6444748076e4975be4f.pdf
Evidence Based Women's Health Journal
2090-7265
2090-7265
2020
10
2
Comparative study between L-carnitine versus co-enzyme Q10 as an adjuvant therapy to clomiphene resistant pcos women on improving pregnancy rate and prevention of early pregnancy loss
Safaa
Ibrahim
Aim of the work: Compare the effectiveness of L-carnitine versus Co-enzyme Q10 on improving pregnancy rates and decraese the rate of early pregnancy loss in patients with PCO resistant to clomiphene citrate.Setting and Design: A prospective randomized controlled study conducted in infertility clinic of a tertiary care center from June 2017 to June 2019.Patients and Methods: A total of 225 subjects presenting with infertility and diagnosed with PCOS (based on Rotterdam criteria 2003) and resistant to clomiphene citrate were enrolled in the study. Subjects were randomly allocated into three groups. Group A: received clomiphene citrate (CC) only, Group B: received clomiphene citrate plus L-carnitine (2gm). Group C: received clomiphene citrate plus co- enzyme Q10 (200 mg). Main outcome measures include the ovulation rate, cumulative clinical pregnancy rate (CPR) are the primary outcome measures.Results: The ovulation rate was significantly higher among the groups B,C compared to group A (62.5%, 66.6% vs 18.3% respectively). Total number of cases who get pregnant were higher in Group B 35(47.3%), Group C 33(44.6%) compared to Group A 6(8.1%). Cumulative Clinical pregnancy rate was 3%, 49.3%, and 47.8% for Group A, Group B, and Group C, respectively. The abortion rate was low in Group B 4 % and significantly lower in Group C 2.7% compared to Group A 6.7%. Conclusion: Adding either L-carnitine or Co-enzyme Q10 to clomiphene citrate in patients with clomiphene-resistant PCOS were beneficial in increasing the quality of ovulation, the clinical pregnancy rate ،also in decreasing the rate of early pregnancy loss.
co-enzyme Q10
induction of ovulation
Infertility
L-carnitine
PCOs
2020
05
01
133
143
https://ebwhj.journals.ekb.eg/article_96097_bed96a5ff7e8acb4e3500a20dfb9e2f6.pdf
Evidence Based Women's Health Journal
2090-7265
2090-7265
2020
10
2
Effect of oxytocin infusion on reducing the blood loss during abdominal myomectomy: A randomized double-Blind controlled trial
Mohammad
Nasr Al-Deen
Ahmed
Nageeb
Mohamed
Elsenity
Othman
Mohammed
Othman
Abbas
Background: Oxytocin is the agent of choice in the prevention of postpartum uterine atony and bleeding. This study aims at assessment of the efficacy of oxytocin infusion on reducing blood loss during abdominal myomectomy.Materials and Methods: The current study was a randomized double-blind controlled trial conducted in a tertiary University Hospital. The study participants were randomized to one of two groups; Group 1 included 30 women received 30 IU of (Oxytocin) in 500 ml normal saline administered during abdominal myomectomy and Group 2 included 30 women received only saline infusion administered during the surgery. The primary outcome is the difference in mean blood loss in both groups.Results: The estimated blood loss was significantly lower among oxytocin group in comparison to the control group as well as significantly higher Postoperative hemoglobin and hematocrit with significantly lower Hematocrit reduction (p<0.001). It showed also significant less blood transfusion in the post operative period among oxytocin group (p=0.044) as well as significantly shorter operative duration, ambulation time and duration of hospital stay.Conclusion:Oxytocin infusion could reduce the blood loss during abdominal myomectomy in the lowest effective and safest dose.
2020
05
01
144
149
https://ebwhj.journals.ekb.eg/article_96099_2277ebd03f129fd8896473b74d574652.pdf
Evidence Based Women's Health Journal
2090-7265
2090-7265
2020
10
2
Impact of prophylactic bilateral salpingectomy on ovarian reserve in women undergoing vaginal hysterectomy: A randomized controlled trial
Ashraf
Nassif
Mohamed
Elnory
Aim: The purpose of this study was to evaluate whether bilateral opportunistic salpingectomy (BOS) in premenopausal women has any detrimental effect on ovarian reserve (OR) and if this increases surgical consequences in women undergoing vaginal hysterectomy (VH)/Non-Descent vaginal hysterectomy (NDVH).Materials and Methods: This prospective, open-label, randomized, multisite, parallel group, concealed allocation, superiority trial was conducted at Benha University Hospital (BUH), and two private centers in El-Qalubia, Egypt, From September 2015 to September 2017. 110 women undergoing VH/NDVH were allocated to adding BOS (intervention group) or not (control group) at 1 : 1 ratio. The primary outcomes were differences in change of serum Anti-müllerian hormone (ΔAMH), serum follicular stimulating hormone (ΔFSH), antral follicular count (ΔAFC), flow index (ΔFI) vascularization index (Δ VI), vascularization flow index (Δ VFI) and calculated ovarian age with OvAge (Δ OvAge), measured preoperatively and at 6 to 8 months postoperatively. The secondary outcomes were surgical outcomes as well as the feasibility of performing BOS at VH/NDVH and hospital stay.Results: Baseline demographic, clinical, hormonal and three-dimensional ultrasound characteristics did not show significant differences between both groups according to both intention to treat (ITT) analysis as well as per protocol (PP) analysis. Also, the groups did not differ significantly regarding operative outcomes such as operative time, operative bleeding and hospital stay according to ITT and PP analyses. The BOS was surgically feasible in 95% (58/61) of tried cases. In both groups the postoperative AMH, AFC, VI, FI, VFI were decreased, while FSH, OvAge were increased. There were no statistically significant differences between intervention and control groups according to ITT as well as PP analyses regarding Δ AMH (P = 0.17), Δ FSH (P = 0.11), ΔAFC (P = 0.07), Δ VI (P = 0.82), Δ FI (P = 0.94),ΔVFI 9 (P = 0.96) and Δ OaAge (P = 0.78).Conclusion: Performing bilateral opportunistic salpingectomy at time of vaginal hysterectomy / Non-descent vaginal hysterectomy did not have a detrimental effect on ovarian reserve as well as surgical consequences when compared with a policy of performing hysterectomy alone. So adding BOS as ovarian cancer risk-reducing surgery appears to be a safe procedure in average OvCa risk premenopausal women undergoing VH/NDVH for benign gynecological indications.
Anti-müllerian hormone
bilateral opportunistic salpingectomy
Non-descent vaginal hysterectomy
ovarian cancer
ovarian reserve
vaginal hysterectomy
2020
05
01
150
161
https://ebwhj.journals.ekb.eg/article_96100_f1ff03e143c0772471bb7f429c73973b.pdf
Evidence Based Women's Health Journal
2090-7265
2090-7265
2020
10
2
Role of cerebro-placental ratio in prediction of perinatal outcome in high-risk pregnancies with intrauterine growth restriction
Mohamed Ahmed
El-Kady
Esraa
Hamdy
Ebtihal
Eltaieb
Introduction: Doppler ultrasound velocimetry of uteroplacental umbilical and fetal vessels has become established method of antenatal monitoring. Cerebroplacental ratio has been studied to predict neonatal outcomes. Aim of the work: Our aim was to assess role of cerebro-placental ratio in prediction of perinatal outcome in high-risk pregnancies with intrauterine growth restriction. Patients and Methods: In this study was held in Ain Shams university maternity hospital which included 60 high risk pregnant women divided in to two groups: Group I: study group: 30 high risk pregnant women with IUGR, Group II- control group: 30 high risk pregnant women without IUGR. Results: The current study showed that among patients with IUGR and low CPR, 17 (56.7%) had CS for fetal distress, 12 (40.0%) had neonate with low APGAR, 13 (43.3%) had neonatal meconium aspiration, 6 (20.0%) had neonatal Hypoxic ischemic Encephalopathy, 15 (50.0%) had neonate need NICU admission, 3 (10.0%) had neonatal death, 1 (3.3%) had neonatal still birth. The current study showed that among patients without IUGR and low CPR, 8 (26.7%) had CS for fetal distress, 5 (16.7%) had neonate with low APGAR, 4 (13.3%) had neonatal meconium aspiration, 1 (3.3%) had neonatal Hypoxic ischemic Encephalopathy, 5 (16.7%) had neonate need NICU admission, 1 (3.3%) had neonatal death, 0 (0.0%) had neonatal still birth. Conclusion: Cerebro -placental ratio has high predictive value of perinatal outcome in high risk pregnancy with intrauterine growth restriction.
2020
05
01
162
169
https://ebwhj.journals.ekb.eg/article_96104_4dce1f89676c2e494bd90dd601f0bfa8.pdf
Evidence Based Women's Health Journal
2090-7265
2090-7265
2020
10
2
Assessment of Sexual Troubles in Egyptian Women with Female Genital Mutilation
Mohamad
Abdelhafeez
Mohamad
Salem
manal
eisa
Aim: The aim of this study was to detect the most common causative organism causing neonatal sepsis in women suffered preterm prelabour rupture of membranes and if it is different from that of the maternal genital swab.Materials and Methods: This study was carried out on 200 pregnant women with PPROM at gestational age between 23 weeks plus 6 days to 28 weeks. Genital swabs were taken for microbiological study and all women were managed conservatively. After delivery, buccal and nasal swab were taken from the neonates and the detected organism(s) were correlated with those detected from the mothers' swabs. Also, neonatal outcome was studied regarding incidence of neonatal sepsis, Neonatal Intensive Care Unit) admission and neonatal mortality.Results: From the 200 enrolled cases and their neonates, there were thirty-three neonates (16.5%) that were admitted to the NICU with twenty-one neonates (67.8%) of them suffering neonatal sepsis. Only thirteen neonates (61.9%) of those who had suffered sepsis shared the same organisms with their mothers. The other eight cases (38.1%) had different organisms. The most frequent organism regarding maternal vaginal swabs was Escherichia coli followed by Group B Streptococci sharing the same frequency with non-hemolytic Streptococci, Staphylococcus aureus and Group A streptococci sharing the same frequency with Klebsiella species.Conclusion: E-coli is the most common causative organism for neonatal sepsis in PPROM before 28 weeks of gestation.
Anorgasmia
clitoris
female genital mutilation
FSFI
sexual dysfunction orgasm
sexual function
2020
05
01
170
175
https://ebwhj.journals.ekb.eg/article_96105_e243dd19b53cab170d9df9c7263a5ca5.pdf
Evidence Based Women's Health Journal
2090-7265
2090-7265
2020
10
2
Relation between anti-thyroid peroxidase antibody and recurrent pregnancy loss: A case control study
Mohamed
Ali
Rehab
Abdel Rahman
Nancy
Wahba
Mohamed
Gaber
Background: Thyroid dysfunction and autoimmunity are relatively common clinical scenario in women within reproductive age group and have been correlated and linked to a spectrum of adverse pregnancy outcomes such as recurrent miscarriage. Aim: To investigate the correlation and linkage between anti-TPO antibody and recurrent miscarriage.Materials and Methods: This case control observational research study was conducted on 90 pregnant female out which 45 with history of recurrent miscarriage were cases and 45 without such history were controls.Results: The mean age of control group was 25.29 while it was 26.69 in cases group. The prevalence of anti-tpo antibody positivity in the study group was 18.8%.out of 90 pregnant female ;17 were positive for anti-tpo antibody. The prevalence of thyroid autoimmunity in pregnant women with recurrent abortion was (37.8%) while it was (0%) in the healthy group (P=0.0). Conclusion:There was significant relationship between anti thyroid antibody positivity and recurrent miscarriage. Thyroid autoimmunity can be considered as risk marker for recurrent miscarriage.
Anti-tpo antibody
Pregnancy
recurrent miscarriage
2020
05
01
176
180
https://ebwhj.journals.ekb.eg/article_96106_70c913bb89347c77d8009db4b16cb828.pdf