eng
Evidence Based Women’s Health Society
Evidence Based Women's Health Journal
2090-7265
2090-7257
2017-08-01
7
3
91
99
10.21608/ebwhj.2017.5059
5059
Original Article
Hyperemesis gravidarum and early new-born outcomes
Background: Hyperemesis gravidarum (HG) represents a more severe degree of nausea and vomiting of pregnancy and is potentially lethal if not treated well. HG is defined as persisting nausea and vomiting leading to dehydration, weight loss and nutritional deficiencies and was reported to be associated with poor perinatal outcome.Aim: To evaluate the effect of HG on the perinatal outcome.Patients and Methods: The study was conducted at Suez Canal University Hospitals, Ismailia at outpatient clinic from October 2015 to January 2017. 132 patients were randomly selected with evidence of HG, the study group, and 137 women with no evidence of HG were the control group. Preterm birth, low birth weight, Apgar score Results: The Apgar score at 5 minutes of birth was the only outcome showed significant difference between the both groups (P value <0.001) while other mentioned perinatal outcomes were of insignificant difference. Also such significant difference in the Apgar score was more related to the maternal weight gain.Conclusion: Apgar score at 5 minutes of birth could be affected by HG if associated with poor maternal weight gain
https://ebwhj.journals.ekb.eg/article_5059_a51706681dce69b92c21fc186b177e5f.pdf
Hyperemesis gravidarum
nausea and vomiting in pregnancy
pregnancy outcome
eng
Evidence Based Women’s Health Society
Evidence Based Women's Health Journal
2090-7265
2090-7257
2017-08-01
7
3
105
117
10.21608/ebwhj.2017.5060
5060
Original Article
First –trimester in comparison to second trimester detailed anomaly scan in diagnosis of fetal congenital anomalies in pregnant women with pregestational diabetes
Background: Pregestational Diabetes mellitus increases the risk of fetal congenital Structural abnormalities .Ultrasonographic evaluation of a fetus of pregnant mothers.With pregestational D.M can be done early in first trimester (starting from 11 weeks + 1 day) also in second trimester scan we can diagnose another abnormalities later in pregnancy.Aim of the work : Assessment of the accuracy of first Trimester anomaly scan versus the second Trimester anomaly scan in Diabetic pregnant women. In diagnosis of fetal congenital anomalies.Methods : 2D and 3 D Ultrasound was performed to 2500 pregnant women With pregestational D.M and to 300 pregnant women with no medical disorders both in first trimester(11weeks + 1 day ) And then in second trimester (at 18 weeks till 24 weeks) -Tei index (myocardial performance index) was also done HbA1c was done .Results : Our study indicates a higher percent of congenital anomalies in diabetic pregnant Mothers than non diabetic pregnant women.Conclusion: From our study, we concluded that 1st trimester scan offers an early noninvasive method of prenatal diagnosis of fetal congenital abnormalities. Especially 1st trimester scan, we can diagnose major brain anomalies (Anencephaly , Acrania), anterior abdominal wall defects (Gastroschisis, omphalocele) neural tube defects ( encephaloce) some renal anomalies (renal agenesis) But other structural fetal congenital anomalies needs a detailed 2nd trimester scan.
https://ebwhj.journals.ekb.eg/article_5060_91a910a5c5465fceb08c80cea069b9e7.pdf
early scan
fetal anomalies
pregestational diabetes
eng
Evidence Based Women’s Health Society
Evidence Based Women's Health Journal
2090-7265
2090-7257
2017-08-01
7
3
118
122
10.21608/ebwhj.2017.5061
5061
Original Article
Interleukin-6 gene polymorphisms and its relation to spontaneous preterm labour among Egyptian women
Objective: to verify the possible relationship between interleukin-6 (IL-6) promoter -174 polymorphisms and spontaneous preterm birth between 28 and 37 weeks of gestation among Egyptian women.Methods: This is a multicenter case control study comprising 184 pregnant women between 28 and 36+6 weeks of gestational age (GA) at termination, divided into a study group including sixty one women with established preterm labor, and another 123 pregnant women at full term represented the control group. Venous blood samples were taken for DNA extraction using QIAamp DNA Blood Mini Kit for IL-6 promoter polymorphism status.Results: Among the preterm delivering women, 65.6%, 26.2% and 8.2% had C/C, G/C and G/G variants, respectively. On the other hand, within the 123 women representing the control group, we found 84.6%, 15.4% who showed C/C and G/C variants. There was no single woman showing the G/G variant. This was statistically significant (P < 0.05).Conclusion: The genetic make-up of interleukin-6 production may have a role in the etiology of preterm labour among Egyptian women of Middle Eastern ethnicity. PCR for IL-6 polymorphism could be proposed as one of the predictors for preterm labor, however, in a multi-factorial problem like preterm labor it is not the only predictor tool.
https://ebwhj.journals.ekb.eg/article_5061_8ff53d3067485556987b6ba2e480c9e6.pdf
Egyptian Women
gene polymorphisms
interleukin -6
preterm labor
eng
Evidence Based Women’s Health Society
Evidence Based Women's Health Journal
2090-7265
2090-7257
2017-08-01
7
3
100
104
10.21608/ebwhj.2017.5062
5062
Original Article
The correlation between helicobacter pylori Infection, hyperemesis gravidarum, and anemia among pregnant females … Effect of treatment
Objective: The aim of this study was to detect the relationship between Helicobacter pylori (H.pylori) infection and pregnancy related disorders: anemia and hyperemesis gravidarum.Study Design: It was a prospective study. Randomized control study.Patients and methods: In our study pregnant women between 6-12 weeks of gestation were divided into 3 groups: control group of 144 patients, hyperemesis gravidarum group of 88 patients, anemia group of 128 patients. Seropositivity for H.pylori was studied in each group. H.pylori positive patients in anemia group were divided into two groups and asked to return in second trimester and one group of them recieved treatment of anemia alone, while the other one recieved treatment of anemia and H.pylori treatment and the change in hemoglobin (Hb) levels was detected in both groupsResults: The percentage of H.pylori seropositive patients in the control group was 45.8%, in hyperemesis group 86.4% while in the anemia group was 84.4% (p value< 0.001).The change in Hb in the group which was given treatment of anemia alone was 0.936± 0.325 while it was 1.438± 0.354 in the group which was given treatment for anemia plus treatment to eradicate H.pylori (P value <0.001).Conclusions: Our study showed strong association between H.pylori infection and hyperemesis gravidarum and we suggested screening of H.pylori in cases with hyperemesis especially in severe cases. And we founded great benefit in eradication of H.pylori infection with treatment of anemia in pregnant women.
https://ebwhj.journals.ekb.eg/article_5062_9b594a2f2991201f03cede0b4286e940.pdf
Anemia
Helicobacter pylori
Hyperemesis gravidarum