Impact of COVID-19 Infection on the Maternal and Perinatal Outcome of Pregnancies Associated with Preeclampsia

Document Type : Original Article

Authors

Obstetrics and Gynecology Department, Faculty of Medicine, MINIA University, Egypt

Abstract

Objectives: To compare the severity and complications of preeclampsia in the presence and absence of COVID-19 infection
Methods: A cross-sectional study was carried out at Minia Governate isolation Hospitals which have a standard procedure
for monitoring and testing COVID-19. The study enrolled 345 pregnant women after considering eligibility criteria. One
hundred fifteen cases were positive for COVID-19 infection compared with randomly chosen control cases with a ratio of 1:2
of COVID-19-negative pregnant women.
Result: The incidence of preeclampsia in COVID-19-infected pregnant women was 31.3% (36 cases), while 42 cases in the
non-COVID-19 group had preeclampsia with an incidence of 18.3%. There was a high incidence of maternal complications
in the study group (ICU admission incidence was 72.2% versus 45.2%, and maternal mortality was 41.6% versus 38%). Fetal complications were higher in the study group.
Conclusion: The development of preeclampsia in COVID-19 patients is associated with hazardous maternal and fetal
outcomes. It increases the need for ICU admission, invasive ventilation support, maternal and perinatal mortality.

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